Assessment of white matter injury and outcome in severe brain trauma: a prospective multicenter cohort

D Galanaud, V Perlbarg, R Gupta… - The Journal of the …, 2012 - pubs.asahq.org
Background Existing methods to predict recovery after severe traumatic brain injury lack
accuracy. The aim of this study is to determine the prognostic value of quantitative diffusion
tensor imaging (DTI). Methods In a multicenter study, the authors prospectively enrolled 105
patients who remained comatose at least 7 days after traumatic brain injury. Patients
underwent brain magnetic resonance imaging, including DTI in 20 preselected white matter
tracts. Patients were evaluated at 1 yr with a modified Glasgow Outcome Scale. A composite …
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